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  1  definition  found 
  From  Webster's  Revised  Unabridged  Dictionary  (1913)  [web1913]: 
  Buffy  \Buff"y\,  a.  (Med.) 
  Resembling,  or  characterized  by  buff. 
  {Buffy  coat},  the  coagulated  plasma  of  blood  when  the  red 
  corpuscles  have  so  settled  out  that  the  coagulum  appears 
  nearly  colorless.  This  is  common  in  diseased  conditions 
  where  the  corpuscles  run  together  more  rapidly  and  in 
  denser  masses  than  usual.  --Huxley.